【个人简介】

桂海龙，男，1988年7月，陕西咸阳市人，中共党员，博士，讲师，硕士研究生导师，沈阳市拔尖人才，辽宁大学（营口）城市研究院院长。本科硕士均毕业于西北农林科技大学食品专业，博士毕业于沈阳农业大学食品科学与工程专业。参与国家自然科学基金和横向课题等多个项目，主持辽宁省项目3项。曾在企业从事功能食品和婴幼儿配方乳粉研发工作。近5年发表SCI共11篇，以第一（含共同）作者身份在《Critical Reviews in Food Science and Nutrition》、《Food Chemistry》、《Frontiers in Plant Science》等杂志上发表SCI论文4篇，其中高被引论文1篇，累计影响因子达35.8，授权中国发明专利1项，《Journal of Future Foods》青年编委、中国食品科学技术学会会员。

【研究领域及主要项目】

主要研究领域：

1.天然活性产物提取、分离及其构效关系。

2.功能因子体外稳态加工及协同增效。

3.生物大分子纳米载体构建，分子对接及其动力学模拟。

【学术成果】

学术论文

1. Hailong Gui, Lijun Sun, Ruihai Liu, Xu Si, Dongnan Li, Yuehua Wang, Chi Shu, Xiyun Sun, Qiao Jiang, Yanyan Qiao, Bin Li, Jinlong Tian. Current knowledge of anthocyanin metabolism in the digestive tract: absorption, distribution, degradation, and interconversion. Critical Reviews in Food Science and Nutrition, 2022, 1-14. (第一作者SCI顶刊，中科院/JCR 1区，IF=11.176高被引).

2. Hailong Gui, Jian Dai, Jinlong Tian, Qiao Jiang, Ye Zhang, Guangyu Ren, Baoge Song, Mingshuang Wang, Mihereban Saiwaidoula, Wenjiang Dong, Bin Li. The isolation of anthocyanin monomers from blueberry pomace and their radical-scavenging mechanisms in DFT study. Food Chemistry, 2023, 418:135872. (第一作者SCI顶刊，中科院/JCR 1区，IF=9.231).

3. Hailong Gui, Qiao Jiang, Jinlong Tian, Zhihuan Zang, Shufang Yang, Yiyun Yang, Meilin Xin, Min Zhao, Jian Dai, Bin Li. Interaction and binding mechanism of cyanidin-3-O-glucoside to lysozyme in varying pH conditions: Multi-spectroscopic, molecular docking and molecular dynamics simulation approaches. Food Chemistry, 2023, 425:136509. (第一作者SCI顶刊，中科院/JCR 1区，IF=9.231).

4. Jian Dai#, Hailong Gui#, Feng Shen, Yuying Liu, Minsong Bai, Jinfeng Yang, Houjun Liu, Peiyu Luo, Xiaori Han, Kadambot Siddique. Fertilizer 15N balance in a soybean–maize–maize rotation system based on a 41-year long-term experiment in Northeast China. Frontiers in Plant Science, 2023, 14. 1105131. (共一作者SCI，JCR 1区，IF=6.28).

5. Xu Xie, Jinlong Tian, Yuehua Wang, Chi Shu, Hailong Gui, Zhen Cheng, Zeming Wang, Ziqi Song, Qilin Tian, Bosu Wen, Bin Li. Comparison of the content of taste and nutrition-related non-volatile compounds in cultivated and wild blueberry varieties in Northeast China. Food Chemistry: X, 2025. (中科院2区，IF=5.1).

6. Qiao Jiang, Yubo Liu, Xu Si, Li Wang, Hailong Gui, Jinlong Tian, Huijun Cui, Hongzhou Jiang, Wenjiang Dong, Bin Li. Potential of Milk-Derived Extracellular Vesicles as Carriers for Oral Delivery of Active Phytoconstituents. Annual Review of Food Science and Technology, 2024, 15: 431-454. (中科院1区，IF=11.1).

7. Siyi Tang, Xu Si, Zhihuan Zang, Hailong Gui, Xu Xie, Liang Wang, Ying He, Baoru Yang, Bin Li. Mildly preheating induced conformational changes of soy protein isolates contributed to the binding interaction with blueberry anthocyanins for stabilization. Food Hydrocolloids, 2024, DOI: 10.1016/j.foodhyd.2024.110209. (中科院1区，IF=10.7).

8. Qiao Jiang, Li Wang, Jinlong Tian, Weijia Zhang, Huijun Cui, Hailong Gui, Zhihuan Zang, Bin Li, Xu Si. Food-derived extracellular vesicles: natural nanocarriers for active phytoconstituents in new functional food. Critical Reviews in Food Science and Nutrition, 2024, 64(32): 11701-11722. (中科院1区，IF=8.4).

9. Qiao Jiang, Li Wang, Xu Si, Yuanyuan Bian, Weijia Zhang, Huijun Cui, Hailong Gui, Ye Zhang, Bin Li, Dehong Tan. Pterostilbene antagonizes homocysteine-induced oxidative stress, apoptosis and lipid deposition in vascular endothelial cells. Food Science and Human Wellness, 2023, 12(5): 1683-1692. (中科院1区，IF=5.4).

10. Qiao Jiang, Li Wang, Xu Si, Jin-Long Tian, Ye Zhang, Hai-Long Gui, Bin Li, De-Hong Tan. Current progress on the mechanisms of hyperhomocysteinemia-induced vascular injury and use of natural polyphenol compounds. European Journal of Pharmacology, 2021, 905: 174168. (中科院2区，IF=4.4).

11. Yiwen Bao, Mingshuang Wang, Xu Si, Dongnan Li, Hailong Gui, Qiao Jiang, Jiaxin Li, Shufang Yang, Yiyun Yang, Zhongxia Li, Bin Li. Customized development of 3D printed anthocyanin-phycocyanin polychromatic oral film via chondroitin sulfate homeostasis: A platform based on starch and κ-carrageenan. International Journal of Biological Macromolecules, 2025, 318: 135628. (中科院1区，IF=8.0).

专利

1.一种蝉花酱油（第一发明人，ZL 201610182543.9）。

【教学工作】

本科生课程：《食品工程原理》、《食品工程原理课程设计》、《文献检索》、《认识实习》、《毕业实习》等研究生课程：《大分子模拟与计算》。

【联系方式】

邮箱：guihailong@lnu.edu.cn